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We report a HER2 T798I gatekeeper mutation in a patient with HER2 L869R-mutant breast cancer with acquired resistance to neratinib.Laboratory studies suggested that HER2 L869R is a neratinib-sensitive, gain-of-function mutation that upon dimerization with mutant HER3 E928G, also present in the breast cancer, amplifies HER2 signaling.

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89-year-old Redwood City Widow Wins in Court After signing what Pauline Reade believed to be a repair permit for her backyard shed, Fetuu Tupoufutuna, an iterant handyman, stole $600,000 in the form of a home equity loan against her real estate holdings. After

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Aug 21, 2019 · 1,931 Likes, 28 Comments - Arizona State University (@arizonastateuniversity) on Instagram: “It's a big day tomorrow. Take some time to self-care today, whatever that means for you! ♥️💛 . . .…”

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In October 2000, a police officer shot and killed unarmed 17-year-old Asel Asleh. His story is tragically familiar for Americans, but Asel was not killed in Ferguson, New York City, Atlanta, or Minneapolis. Asel was a Palestinian teenager who was...

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